Introduction. Aging is a complex, multifactorial process that affects every organ in the body, including the skin. 1,2 Clinically, aged skin is characterized as thin, dry, and pale, with noticeable wrinkles and decreased elasticity. 3,4 The histological changes associated with aging in skin include the accumulation of elastotic material in the papillary and mid-dermis, a process known as solar ...
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