Acetylcholine is the major excitatory neurotransmitter at nematode neuromuscular junctions, and more than a third of the cells in the C. elegans nervous system release acetylcholine. Through a combination of forward genetics, drug-resistance selections, and genomic analysis, mutants have been identified for all of the
Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals, and humans, as a neurotransmitter—a chemical message released by nerve cells to send signals to other cells, such as neurons, muscle cells, and gland cells. Its name is derived from its chemical structure: it is an ester of acetic acid and choline.
acetylcholine receptor antibodies . Most patients with myasthenia gravis have abnormally elevated levels of these antibodies. Recently, a second antibody — called the anti -MuSK antibody — has been found in about 30 to 40 percent of individuals with myasthenia gravis who do not have acetylcholine receptor antibodies .
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